A common type of vision loss after stroke or traumatic brain injury, a scotoma is an island of visual field loss (blindness) or impaired vision surrounded by relatively normal vision. The eyes of mammals naturally have a small scotoma (blind spot) that we normally don’t notice. However, a wide range of diseases and injuries can cause a pathological scotoma. For example, a scotoma can be a sign of optic nerve damage sustained during a stroke or brain injury. Previously considered untreatable, new research has led to exciting developments in treating scotoma.